Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 7/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.48 |
| ▸ | PARP1 | P09874 | 5/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984279 | 0.91 | SMN1; SMN2 (0.47) | TNKSTNKS2PARP1HPGDALDH1A1 | |
| SCHEMBL7988517 | 0.91 | ABCC8 (0.47) | TNKSTNKS2PARP1ABCC8KCNJ11 | |
| SCHEMBL7974486 | 0.89 | SMN1; SMN2 (0.50) | TNKSTNKS2PARP1ABCC8KCNJ11 | |
| SCHEMBL7984930 | 0.88 | ABCC8 (0.47) | TNKSTNKS2PARP1ABCC8KCNJ11 | |
| SCHEMBL7985164 | 0.88 | KMT2A (0.46) | TNKSTNKS2PARP1HPGDALDH1A1 | |
| SCHEMBL7992261 | 0.88 | TNKS (0.43) | TNKSTNKS2PARP1ABCC8KCNJ11 | |
| SCHEMBL7984864 | 0.88 | ABCC8 (0.44) | TNKSTNKS2PARP1ABCC8KCNJ11 | |
| SCHEMBL7986518 | 0.86 | SMN1; SMN2 (0.53) | TNKSTNKS2HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7974505 | 0.86 | SMN1; SMN2 (0.55) | TNKSTNKS2HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7985270 | 0.85 | ALDH1A1 (0.44) | HPGDALDH1A1SMN1; SMN2KMT2AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |