Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974486 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7985321 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7986235 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7975265 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7988785 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7984971 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2AHIF1A | |
| SCHEMBL8056964 | 0.83 | CNOT7 (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7984883 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7985355 | 0.83 | GAA (0.56) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL7988680 | 0.83 | HPGD (0.46) | SMN1; SMN2ALDH1A1HPGDKMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |