Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PARN | O95453 | 1/20 | 0.47 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985707 | 0.84 | CYP11B2 (0.47) | ADORA3PARNCNOT7P2RX7HPGD | |
| SCHEMBL7985228 | 0.84 | CXCR2 (0.50) | PARNCNOT7P2RX7HPGDGAA | |
| SCHEMBL7985346 | 0.83 | CNOT7 (0.52) | PARNCNOT7P2RX7HPGDGAA | |
| SCHEMBL7974513 | 0.83 | ADORA3 (0.53) | ADORA3P2RX7HPGDGAAKDM4E | |
| SCHEMBL7987785 | 0.82 | PARN (0.47) | PARNCNOT7HPGDKDM4EALDH1A1 | |
| SCHEMBL7984366 | 0.82 | CNOT7 (0.53) | PARNCNOT7HPGDALDH1A1 | |
| SCHEMBL7975254 | 0.82 | CNOT7 (0.55) | PARNCNOT7HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7992068 | 0.81 | CNOT7 (0.52) | PARNCNOT7HPGDALDH1A1 | |
| SCHEMBL7985687 | 0.81 | CNOT7 (0.55) | PARNCNOT7HPGDKDM4EALDH1A1 | |
| SCHEMBL7987705 | 0.80 | CNOT7 (0.51) | PARNCNOT7HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |