Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985702 | 0.84 | HPGD (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7985230 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7985339 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7974521 | 0.83 | ADORA3 (0.48) | ADORA3ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL7987778 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL9905498 | 0.82 | HPGD (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7975251 | 0.82 | SMN1; SMN2 (0.60) | ADORA3SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL7984363 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7985680 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7992062 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |