Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | PARN | O95453 | 1/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985707 | 0.96 | CYP11B2 (0.47) | CXCR2PARNCNOT7HPGDKDM4E | |
| SCHEMBL7974480 | 0.90 | GUSB (0.50) | PARNCNOT7HPGDKDM4EALDH1A1 | |
| SCHEMBL7985350 | 0.90 | GAA (0.48) | PARNCNOT7HPGDGAAMAPT | |
| SCHEMBL7975271 | 0.89 | CNOT7 (0.56) | CXCR2PARNCNOT7HPGDALDH1A1 | |
| SCHEMBL7974021 | 0.89 | TP53 (0.51) | PARNCNOT7ALDH1A1GAAMAPT | |
| SCHEMBL7974586 | 0.89 | GAA (0.52) | PARNCNOT7GAAMAPTP2RX7 | |
| SCHEMBL7987774 | 0.89 | CNOT7 (0.46) | PARNCNOT7HTTNPSR1GUSB | |
| SCHEMBL7984461 | 0.86 | CNOT7 (0.52) | CXCR2PARNCNOT7HPGDALDH1A1 | |
| SCHEMBL7975135 | 0.86 | CNOT7 (0.52) | PARNCNOT7HPGDKDM4EALDH1A1 | |
| SCHEMBL7988605 | 0.86 | GUSB (0.48) | PARNCNOT7GUSBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |