Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974543 | 1.00 | ERN1 (0.51) | ERN1GABRA3GABRA2GABRB2BACE1 | |
| SCHEMBL8446850 | 0.83 | GABRA3 (0.51) | ERN1GABRA3GABRA2GABRB2BACE1 | |
| SCHEMBL7991886 | 0.80 | ERN1 (0.59) | ERN1GABRA3GABRA2GABRB2BACE1 | |
| SCHEMBL7991883 | 0.80 | ERN1 (0.59) | ERN1GABRA3GABRA2GABRB2BACE1 | |
| SCHEMBL13528990 | 0.78 | CYP1A2 (0.62) | MAPTKDM4EALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9148376 | 0.76 | LTB4R (0.49) | KDM4EALDH1A1NPC1RAB9AABL1 | |
| SCHEMBL8416685 | 0.76 | LTB4R (0.49) | KDM4EALDH1A1NPC1RAB9AABL1 | |
| SCHEMBL9473131 | 0.74 | ALDH1A1 (0.45) | BACE1MAPTAPPKDM4EALDH1A1 | |
| SCHEMBL7988046 | 0.74 | ERN1 (0.65) | ERN1GABRA3GABRA2GABRB2BACE1 | |
| SCHEMBL7988050 | 0.74 | ERN1 (0.65) | ERN1GABRA3GABRA2GABRB2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010024798-A1 | Biomimetic combinatorial synthesis | SHAIR MATTHEW D (US) | 2001-09-27 | — | — | US | disclosed |
| WO-1999064379-A2 | BIOMIMETIC COMBINATORIAL SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010024798-A1 | Biomimetic combinatorial synthesis | COASY, BBOX1, CYP4B1 | ERN1 1036/4885GABRA3 1680/4885GABRA2 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.