Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971427 | 0.87 | CYP1A2 (0.36) | CYP4F2CYP4A11KMT2AALDH1A1 | |
| SCHEMBL7974479 | 0.87 | IMPDH1 (0.37) | KMT2AALDH1A1MEN1MAPK1POLB | |
| SCHEMBL7972666 | 0.83 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL7974393 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL7974447 | 0.79 | CYP4F2 (0.43) | CYP4F2CYP4A11KMT2AALDH1A1MEN1 | |
| SCHEMBL7971422 | 0.78 | RAB9A (0.48) | KMT2AALDH1A1MEN1L3MBTL1LMNA | |
| SCHEMBL798044 | 0.74 | CYP4F2 (0.53) | CYP4F2CYP4A11KMT2AALDH1A1MEN1 | |
| SCHEMBL22098179 | 0.73 | CYP4F2 (0.63) | CYP4F2CYP4A11KMT2AALDH1A1MEN1 | |
| SCHEMBL3492496 | 0.70 | CYP4F2 (0.49) | CYP4F2CYP4A11KMT2AALDH1A1MEN1 | |
| SCHEMBL882521 | 0.68 | CYP4F2 (0.47) | CYP4F2CYP4A11KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |