Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974061 | 0.89 | CNOT7 (0.42) | CNOT7PARNKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7988188 | 0.89 | CNOT7 (0.44) | CNOT7PARNKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7974647 | 0.88 | CNOT7 (0.51) | CNOT7PARNKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7974492 | 0.85 | ABCC8 (0.47) | ABCC8KCNJ11CNOT7PARNKMT2A | |
| SCHEMBL7984195 | 0.84 | HPGD (0.45) | ABCC8KCNJ11KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7987364 | 0.84 | TNKS (0.46) | ABCC8KCNJ11CNOT7PARNSMN1; SMN2 | |
| SCHEMBL7991661 | 0.83 | ABCC8 (0.45) | ABCC8KCNJ11CNOT7PARNKMT2A | |
| SCHEMBL7992270 | 0.82 | ABCC8 (0.43) | ABCC8KCNJ11CNOT7PARNNR1H4 | |
| SCHEMBL7984880 | 0.82 | P2RX7 (0.46) | CNOT7PARNKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7974312 | 0.82 | HPGD (0.45) | CNOT7PARNKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |