Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964612 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7978004 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL6579154 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7975932 | 0.82 | ALOX5 (0.42) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7976008 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL6576756 | 0.81 | ESR1 (0.42) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL27387414 | 0.81 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL6579500 | 0.77 | TTR (0.47) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL8004161 | 0.77 | TTR (0.47) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL7974971 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |