Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7984673 | 0.99 | ABCC8 (0.46) | ABCC8KCNJ11NR1H4EPHX2SCD | |
| SCHEMBL7991370 | 0.86 | KDM4E (0.51) | PKMGAATSHR | |
| SCHEMBL7988530 | 0.85 | SMN1; SMN2 (0.46) | SCDPKMGAATSHRCYP11B1 | |
| SCHEMBL7987743 | 0.83 | SCD (0.50) | SCDPKMGAATSHRCYP11B1 | |
| SCHEMBL7987690 | 0.82 | PKM (0.43) | PKMGAATSHRCYP11B1CYP11B2 | |
| SCHEMBL5483136 | 0.81 | PKM (0.59) | PKMGAATSHRCYP11B1CYP11B2 | |
| SCHEMBL7987441 | 0.81 | MEN1 (0.49) | GAACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7987445 | 0.80 | PKM (0.57) | PKMGAATSHRCYP11B1CYP11B2 | |
| SCHEMBL7984484 | 0.80 | PKM (0.50) | PKMGAATSHRNR1I2CYP11B1 | |
| SCHEMBL7984711 | 0.79 | ABCC8 (0.44) | ABCC8KCNJ11NR1H4EPHX2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |