Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974646 | 0.85 | MAPK14 (0.47) | GAATSHRCXCR2SMN1; SMN2MAPK1 | |
| SCHEMBL7985538 | 0.84 | SMN1; SMN2 (0.43) | GAATSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7988602 | 0.84 | GAA (0.45) | GAATSHRTLR7LMNAMAPK1 | |
| SCHEMBL7974853 | 0.83 | DPP4 (0.48) | GAACYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL7985225 | 0.82 | GAA (0.48) | GAACYP1A2CYP2D6CYP2C19CXCR2 | |
| SCHEMBL7985348 | 0.81 | GAA (0.53) | GAACYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL7988184 | 0.81 | MET (0.42) | TSHRSMN1; SMN2LMNAMAPK1TDP1 | |
| SCHEMBL7975267 | 0.80 | SMN1; SMN2 (0.46) | GAATSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7985870 | 0.80 | GAA (0.50) | GAATSHRMAPK1HSD17B10HPGD | |
| SCHEMBL7974507 | 0.80 | MET (0.46) | GAASMN1; SMN2HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |