Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PARN | O95453 | 1/20 | 0.37 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988184 | 0.93 | MET (0.42) | MAPK14SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL7974060 | 0.91 | SMN1; SMN2 (0.41) | MAPK14SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL7984878 | 0.90 | MAPK14 (0.42) | MAPK14SMN1; SMN2GAAMETMAPT | |
| SCHEMBL7988454 | 0.90 | MAPK14 (0.41) | MAPK14GAAMETCYP11B1CYP11B2 | |
| SCHEMBL7974276 | 0.88 | HTT (0.39) | MAPK14ALDH1A1POLBMAPTMAPK1 | |
| SCHEMBL7974309 | 0.88 | CYP11B1 (0.45) | MAPK14SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL7984199 | 0.88 | NR1H4 (0.44) | MAPK14SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL7973917 | 0.88 | LMNA (0.40) | MAPK14ALDH1A1METHDAC1HDAC6 | |
| SCHEMBL7985538 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7974853 | 0.86 | DPP4 (0.48) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |