Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974639 | 0.83 | CHRM5 (0.46) | RELAKDM4ECYP1A2CYP3A4NPC1 | |
| SCHEMBL8491445 | 0.83 | RELA (0.42) | AHRRELANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29016917 | 0.80 | AHR (0.72) | AHRRELAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL7968100 | 0.80 | PIP4K2A (0.40) | KDM4ENPC1RAB9AABL1 | |
| SCHEMBL14880493 | 0.78 | AHR (0.57) | AHRRELAKDM4ECYP3A4NPC1 | |
| SCHEMBL7968716 | 0.77 | POLB (0.41) | KDM4ECYP1A2CYP3A4NPC1CYP2D6 | |
| SCHEMBL8436212 | 0.77 | CYP11B2 (0.39) | PLAUPLATMAPTCYP19A1 | |
| SCHEMBL18240623 | 0.76 | RELA (0.75) | AHRRELAMAPTALOX5TP53 | |
| SCHEMBL27883 | 0.75 | CA12 (0.65) | AHRRELAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL7958780 | 0.75 | LCK (0.48) | KDM4ECYP1A2HPGDCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |