SCHEMBL7968100

SCHEMBL7968100

FC(F)(F)Oc1ccc([CH]c2cncc(Cl)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PIP4K2A P48426 1/20 0.40
PIM1 P11309 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
KDM4E B2RXH2 1/20 0.36
DHODH Q02127 1/20 0.36
GRIN2B Q13224 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ABL1 P00519 5/20 0.34
PRMT6 Q96LA8 1/20 0.34
CES1 P23141 1/20 0.34
SCN10A Q9Y5Y9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2096214 0.80 CCR6 (0.43) PIM1PIM2KDM4EDHODHGRIN2B
SCHEMBL7975159 0.80 AHR (0.53) KDM4ENPC1RAB9AABL1
SCHEMBL2092050 0.78 PIM1 (0.49) PIM1PIM2KDM4EL3MBTL1
SCHEMBL8491445 0.76 RELA (0.42) PIM1PIM2NPC1RAB9A
SCHEMBL7968716 0.73 POLB (0.41) PIM1KDM4ENPC1RAB9A
SCHEMBL8436212 0.73 CYP11B2 (0.39)
SCHEMBL7958780 0.71 LCK (0.48) KDM4ERAB9AL3MBTL1
SCHEMBL6001487 0.71 PIM1 (0.44) PIM1PIM2GRIN2BKCNH2NPC1
SCHEMBL28825690 0.71 GRIN1 (0.42) GRIN2BL3MBTL1
SCHEMBL543036 0.70 PIM1 (0.46) PIM1PIM2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed