Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046798 | 0.82 | KDM4E (0.47) | HPGDSMN1; SMN2BRD4AURKAKDR | |
| SCHEMBL28468 | 0.81 | KEAP1 (0.57) | SMN1; SMN2HTTBRD4NR3C2NPC1 | |
| SCHEMBL27346378 | 0.79 | KEAP1 (0.55) | SMN1; SMN2HTTBRD4NR3C2NPC1 | |
| SCHEMBL13001968 | 0.79 | HPGD (0.53) | HPGDLMNASMN1; SMN2HTTBRD4 | |
| SCHEMBL10191952 | 0.79 | HPGD (0.53) | HPGDLMNASMN1; SMN2HTTBRD4 | |
| SCHEMBL23541117 | 0.78 | ALOX15 (0.56) | HPGDLMNASMN1; SMN2HTTBRD4 | |
| SCHEMBL10294867 | 0.78 | HPGD (0.47) | HPGDLMNASMN1; SMN2HTTBRD4 | |
| SCHEMBL11655851 | 0.78 | HTR6 (0.57) | HPGDLMNASMN1; SMN2HTTBRD4 | |
| SCHEMBL21240922 | 0.78 | HPGD (0.47) | HPGDLMNASMN1; SMN2HTTBRD4 | |
| SCHEMBL9993451 | 0.78 | ALDH1A1 (0.53) | HPGDLMNASMN1; SMN2HTTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |