Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983842 | 0.79 | GAA (0.38) | PDCD1CD274POLB | |
| SCHEMBL7994077 | 0.74 | PDCD1 (0.46) | PDCD1CD274APOBEC3G | |
| SCHEMBL7975381 | 0.73 | SMN1; SMN2 (0.49) | POLB | |
| SCHEMBL7994549 | 0.68 | LMNA (0.45) | POLB | |
| SCHEMBL16957698 | 0.65 | PDCD1 (0.50) | PDCD1CD274APOBEC3G | |
| SCHEMBL7997459 | 0.65 | PDCD1 (0.37) | PDCD1CD274APOBEC3G | |
| SCHEMBL7963854 | 0.65 | PDCD1 (0.37) | PDCD1CD274POLBAPOBEC3G | |
| SCHEMBL7994239 | 0.64 | CYP1A2 (0.49) | PDCD1CD274POLBAPOBEC3G | |
| SCHEMBL6424004 | 0.62 | PDCD1 (0.64) | PDCD1CD274APOBEC3G | |
| SCHEMBL7994393 | 0.61 | ALDH1A1 (0.42) | PDCD1CD274POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |