Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997459 | 0.88 | PDCD1 (0.37) | PDCD1CD274APOBEC3GS100A4CDC25A | |
| SCHEMBL16957698 | 0.79 | PDCD1 (0.50) | PDCD1CD274APOBEC3GALDH1A1LMNA | |
| SCHEMBL7963854 | 0.78 | PDCD1 (0.37) | PDCD1CD274APOBEC3GKDM4EMAPK1 | |
| SCHEMBL7994239 | 0.77 | CYP1A2 (0.49) | PDCD1CD274APOBEC3GS100A4CDC25B | |
| SCHEMBL25413385 | 0.76 | MAPK1 (0.41) | APOBEC3GS100A4CDC25ACDC25BSTAT3 | |
| SCHEMBL7974535 | 0.75 | BACE1 (0.37) | KDM4EMAPK1FGFR1 | |
| SCHEMBL6424004 | 0.75 | PDCD1 (0.64) | PDCD1CD274APOBEC3GCYP1A2MEN1 | |
| SCHEMBL7994388 | 0.74 | SMN1; SMN2 (0.40) | PDCD1CD274APOBEC3GCYP2D6CYP2C19 | |
| SCHEMBL7994393 | 0.74 | ALDH1A1 (0.42) | PDCD1CD274ALDH1A1LMNAMAPT | |
| SCHEMBL7975333 | 0.74 | PDCD1 (0.37) | PDCD1CD274APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |