Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994038 | 0.88 | HTR7 (0.33) | — | |
| SCHEMBL7994077 | 0.88 | PDCD1 (0.46) | PDCD1CD274APOBEC3GS100A4CDC25A | |
| SCHEMBL10365374 | 0.78 | APOBEC3G (0.57) | PDCD1CD274APOBEC3G | |
| SCHEMBL7974379 | 0.78 | ALDH1A1 (0.34) | PDCD1CD274APOBEC3GKDM4EMAPK1 | |
| SCHEMBL7997463 | 0.73 | PDCD1 (0.32) | PDCD1CD274 | |
| SCHEMBL7975278 | 0.69 | PDCD1 (0.33) | PDCD1CD274APOBEC3GKDM4EMAPK1 | |
| SCHEMBL16957698 | 0.69 | PDCD1 (0.50) | PDCD1CD274APOBEC3G | |
| SCHEMBL7963854 | 0.69 | PDCD1 (0.37) | PDCD1CD274APOBEC3GKDM4EMAPK1 | |
| SCHEMBL7977537 | 0.69 | MAPK1 (0.35) | CDC25ACDC25BKDM4EMAPK1 | |
| SCHEMBL10367304 | 0.68 | APOBEC3G (0.53) | APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |