SCHEMBL7975688

SCHEMBL7975688

N#CCCn1nnnc1[CH]Cc1cc(C(N)=O)c2c(c1)oc1ccccc12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
GLA P06280 1/20 0.33
GHSR Q92847 2/20 0.33
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7962510 0.73 ALDH1A1 (0.38) ALDH1A1GLAKDM4E
SCHEMBL7962305 0.65 GHSR (0.38) ALDH1A1GLAGHSRKDM4EMEN1
SCHEMBL7974057 0.61 GLA (0.34) ALDH1A1GLAGHSRKDM4EMEN1
SCHEMBL7976208 0.61 GHSR (0.48) ALDH1A1GHSRMEN1KMT2A
SCHEMBL2012858 0.61 ALDH1A1 (0.76) ALDH1A1GLAKDM4EKMT2A
SCHEMBL30476189 0.61 ALDH1A1 (0.76) ALDH1A1GLAKDM4EKMT2A
SCHEMBL22114398 0.60 NAALAD2 (0.41) ALDH1A1GLAGHSR
SCHEMBL9653419 0.59 ALDH1A1 (0.49) ALDH1A1GLAKDM4EMEN1KMT2A
Methanesulfonamide SCHEMBL4789997 0.55 ALDH1A1 (0.64) ALDH1A1GLAKDM4EKMT2A
Methanesulfonamide SCHEMBL4790635 0.54 ALDH1A1 (0.62) ALDH1A1GLAKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001077095-A2 DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE NOVARTIS AG (CH) 2001-10-18 WO disclosed