Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | Q9HBH1 | 1/20 | 0.31 | |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990041 | 0.96 | ALDH1A1 (0.34) | ALDH1A1LMNAABCC4MAPTPDF | |
| SCHEMBL7986213 | 0.85 | ALDH1A1 (0.33) | ALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7986818 | 0.84 | EPHX2 (0.32) | ALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7986822 | 0.84 | EPHX2 (0.32) | ALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7989547 | 0.81 | PDF (0.43) | ALDH1A1LMNAABCC4MAPTPDF | |
| SCHEMBL7977102 | 0.81 | PDF (0.44) | ||
| SCHEMBL7976169 | 0.81 | PDF (0.44) | ||
| SCHEMBL7990402 | 0.80 | PSEN1 (0.37) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7990404 | 0.80 | PSEN1 (0.37) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1274009 | 0.79 | SMN1; SMN2 (0.37) | ALDH1A1LMNAABCC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |