Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 7/20 | 0.43 | |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990024 | 0.82 | PDF (0.58) | ||
| SCHEMBL7975796 | 0.81 | ALDH1A1 (0.32) | PDFALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7986213 | 0.81 | ALDH1A1 (0.33) | ALDH1A1LMNAABCC4MAPT | |
| SCHEMBL731079 | 0.80 | PDF (0.38) | PDFALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7990041 | 0.77 | ALDH1A1 (0.34) | PDFALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7990402 | 0.76 | PSEN1 (0.37) | ALDH1A1LMNAMAPT | |
| SCHEMBL7990404 | 0.76 | PSEN1 (0.37) | ALDH1A1LMNAMAPT | |
| SCHEMBL4530365 | 0.76 | PDF (0.37) | PDFALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7986296 | 0.76 | DPP4 (0.49) | PDFALDH1A1LMNAABCC4MAPT | |
| SCHEMBL7986301 | 0.76 | DPP4 (0.49) | PDFALDH1A1LMNAABCC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313164-B1 | TO ENHANCE THE ACTIVITY OF GLUTATHIONE RECLUCTASE; FOR THERAPY AND PROPHYLAXIS OF CARTARACTS | SANKYO COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |
| US-6013663-A | CATARACT THERAPY OR PREVENTION | SANKYO COMPANY, LIMITED (JP) | 2000-01-11 | — | — | US | disclosed |