Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976225 | 0.97 | TDP1 (0.39) | CYP24A1ALDH1A1STAT3HTTSMN1; SMN2 | |
| SCHEMBL7060903 | 0.92 | HTT (0.39) | ALDH1A1STAT3HTTSMN1; SMN2PTGES | |
| SCHEMBL7959874 | 0.92 | MAPT (0.39) | SMN1; SMN2PTGESTDP1 | |
| SCHEMBL7973159 | 0.88 | MAPT (0.39) | SMN1; SMN2PTGESTDP1 | |
| SCHEMBL7969820 | 0.86 | LMNA (0.46) | FKBP1ALMNA | |
| SCHEMBL7975853 | 0.85 | PSMD10 (0.43) | ALDH1A1STAT3GAAKMT2APSMD10 | |
| SCHEMBL7976224 | 0.85 | KMT2A (0.42) | ALDH1A1STAT3SMN1; SMN2GAAKMT2A | |
| SCHEMBL7973259 | 0.85 | FKBP1A (0.43) | CYP24A1ALDH1A1PTGESGAAKMT2A | |
| SCHEMBL7065836 | 0.83 | MAPT (0.41) | SMN1; SMN2PTGESTDP1 | |
| SCHEMBL7973483 | 0.83 | PSMD10 (0.37) | CYP24A1ALDH1A1STAT3KMT2APSMD10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |