Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP7 | P09237 | 3/20 | 0.34 |
| ▸ | MMP12 | P39900 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972978 | 0.96 | KMT2A (0.40) | KMT2AMEN1MAPK1CA12CA2 | |
| SCHEMBL7067274 | 0.91 | KMT2A (0.41) | KMT2AMEN1MAPK1CA12CA2 | |
| SCHEMBL7975853 | 0.89 | PSMD10 (0.43) | KMT2AMEN1CA12CA9RAB9A | |
| SCHEMBL7969622 | 0.89 | TDP1 (0.42) | KMT2AMEN1MAPK1ATMNPC1 | |
| SCHEMBL7959970 | 0.88 | RAB9A (0.36) | KMT2AMEN1MMP1MMP7MMP12 | |
| SCHEMBL7971318 | 0.86 | CTRC (0.40) | MAPK1MMP1MMP7MMP12MMP13 | |
| SCHEMBL7959874 | 0.86 | MAPT (0.39) | ATMSMN1; SMN2 | |
| SCHEMBL7969965 | 0.85 | TSHR (0.43) | MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7976230 | 0.85 | CTRC (0.38) | KMT2AMAPK1CA12CA2CA9 | |
| SCHEMBL7972830 | 0.85 | TDP1 (0.46) | KMT2AMEN1MAPK1ATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |