Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975766 | 1.00 | ALOX5 (0.44) | ALOX5MGLLRAB9ANPC1MEN1 | |
| SCHEMBL7975762 | 1.00 | ALOX5 (0.44) | ALOX5MGLLRAB9ANPC1MEN1 | |
| SCHEMBL7969797 | 0.86 | ALOX5 (0.48) | ALOX5KIF11ALDH1A1MAPTTDP1 | |
| SCHEMBL7969793 | 0.86 | ALOX5 (0.48) | ALOX5KIF11ALDH1A1MAPTTDP1 | |
| SCHEMBL7972776 | 0.86 | ALOX5 (0.48) | ALOX5KIF11ALDH1A1MAPTTDP1 | |
| SCHEMBL7973144 | 0.85 | MGLL (0.39) | ALOX5MGLLRAB9ANPC1MEN1 | |
| SCHEMBL7973141 | 0.85 | MGLL (0.39) | ALOX5MGLLRAB9ANPC1MEN1 | |
| SCHEMBL7972931 | 0.83 | ALOX5 (0.47) | ALOX5RAB9ANPC1MEN1KMT2A | |
| SCHEMBL7969766 | 0.83 | ALOX5 (0.47) | ALOX5RAB9ANPC1MEN1KMT2A | |
| SCHEMBL7969764 | 0.83 | ALOX5 (0.47) | ALOX5RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291520-B1 | INHIBIT THE ENZYME LIPOXYGENASE; TREATMENT OR ALLEVIATION OF INFLAMMATORY DISEASES, ALLERGIC CONDITIONS AND CARDIOVASCULAR DISEASES | PFIZER | 2001-09-18 | — | — | US | disclosed |
| EP-0559743-B1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE | PFIZER (US) | 1995-03-08 | — | — | EP | disclosed |