SCHEMBL7975911

SCHEMBL7975911

CN(C)CCCc1ccc(C=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.50
CYP2A13 Q16696 1/20 0.50
KCNH2 Q12809 3/20 0.49
SIGMAR1 Q99720 1/20 0.48
ALDH1A1 P00352 2/20 0.47
ALDH3A1 P30838 1/20 0.47
ALDH1A3 P47895 1/20 0.47
LMNA P02545 2/20 0.46
HRH3 Q9Y5N1 2/20 0.45
TAAR1 Q96RJ0 3/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
THRA P10827 2/20 0.41
THRB P10828 2/20 0.41
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14959983 0.93 SIGMAR1 (0.59) CYP2A6CYP2A13KCNH2SIGMAR1HRH3
SCHEMBL7989985 0.88 HRH3 (0.59) CYP2A6CYP2A13KCNH2ALDH1A1ALDH3A1
SCHEMBL9670561 0.83 SIGMAR1 (0.64) KCNH2SIGMAR1LMNAHRH3TAAR1
SCHEMBL15452989 0.81 ALDH1A1 (0.47) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL6811099 0.81 KCNH2 (0.49) KCNH2SIGMAR1ALDH1A1LMNAHRH3
Hydrochloric Acid SCHEMBL31031294 0.79 KCNH2 (0.47) KCNH2SIGMAR1ALDH1A1LMNAHRH3
Water SCHEMBL31031305 0.79 KCNH2 (0.47) KCNH2SIGMAR1ALDH1A1LMNAHRH3
SCHEMBL1825553 0.79 CYP2A6 (0.53) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL28324720 0.79 CDK1 (0.48) CYP2A6SIGMAR1ALDH1A1ALDH3A1ALDH1A3
SCHEMBL7282399 0.79 SIGMAR1 (0.50) CYP2A6CYP2A13KCNH2SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291480-B1 CONTROL OF COCCIDIOSIS IN POULTRY. MERCK & CO., INC. 2001-09-18 US disclosed