SCHEMBL7989985

SCHEMBL7989985

CN(C)CCc1ccc(C=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.59
TAAR1 Q96RJ0 6/20 0.55
CYP2A6 P11509 2/20 0.48
CYP2A13 Q16696 1/20 0.48
ALDH1A1 P00352 2/20 0.45
ALDH3A1 P30838 1/20 0.45
ALDH1A3 P47895 1/20 0.45
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRNA7 P36544 1/20 0.40
KCNH2 Q12809 1/20 0.39
TYR P14679 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975911 0.88 CYP2A6 (0.50) HRH3TAAR1CYP2A6CYP2A13ALDH1A1
SCHEMBL14959983 0.85 SIGMAR1 (0.59) HRH3CYP2A6CYP2A13KCNH2
SCHEMBL18762839 0.82 HRH3 (0.84) HRH3TAAR1ALDH1A1MAPTCHRNA7
SCHEMBL1935603 0.80 LTB4R (0.42) HRH3CYP2A6CYP2A13ALDH1A1ALDH3A1
SCHEMBL11474090 0.80 CYP2A6 (0.41) HRH3CYP2A6CYP2A13ALDH1A1ALDH3A1
SCHEMBL5429778 0.79 CYP2A6 (0.50) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL12126823 0.79 HRH3 (0.59) HRH3TAAR1ALDH1A1LMNACHRNA7
SCHEMBL213342 0.79 HRH3 (0.59) HRH3TAAR1ALDH1A1CHRNA7KCNH2
SCHEMBL5939427 0.79 HRH3 (0.59) HRH3TAAR1ALDH1A1LMNACHRNA7
SCHEMBL6206033 0.79 ALDH1A1 (0.46) HRH3CYP2A6CYP2A13ALDH1A1ALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288061-B1 INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS WELFIDE CORPORATION (JP) 2001-09-11 US disclosed
US-4078062-A ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1978-03-07 US disclosed