Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978033 | 0.81 | CFTR (0.47) | LMNAHTTALDH1A1PKMMAPT | |
| SCHEMBL7988582 | 0.78 | ALDH1A1 (0.45) | LMNAHTTALDH1A1S100A4MAPT | |
| SCHEMBL6579909 | 0.75 | CYP1A2 (0.51) | LMNAHTTMAPTKMT2A | |
| SCHEMBL6579512 | 0.73 | TOP1 (0.40) | LMNAHTTALDH1A1S100A4MAPT | |
| SCHEMBL6579521 | 0.73 | TOP1 (0.40) | LMNAHTTALDH1A1S100A4MAPT | |
| SCHEMBL6582308 | 0.73 | MAPT (0.47) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL8004065 | 0.72 | KDM4E (0.44) | LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7988381 | 0.71 | HTT (0.42) | LMNAHTTALDH1A1PKMS100A4 | |
| SCHEMBL7989452 | 0.70 | MAPT (0.49) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL7998971 | 0.70 | MAPT (0.49) | LMNAHTTALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |