Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579909 | 0.82 | CYP1A2 (0.51) | CFTRLMNAMAPTNOX4KMT2A | |
| SCHEMBL7975939 | 0.81 | LMNA (0.37) | ALDH1A1PKMLMNAMAPTKMT2A | |
| SCHEMBL6582308 | 0.80 | MAPT (0.47) | ALDH1A1LMNAMAPTNOX4KMT2A | |
| SCHEMBL8004065 | 0.78 | KDM4E (0.44) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL7989452 | 0.76 | MAPT (0.49) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7998971 | 0.76 | MAPT (0.49) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7988582 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL7999053 | 0.73 | CYP1A2 (0.51) | CFTRPKMLMNAMAPTNOX4 | |
| SCHEMBL6579512 | 0.71 | TOP1 (0.40) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL6579521 | 0.71 | TOP1 (0.40) | ALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |