SCHEMBL7976049

SCHEMBL7976049

C[C]1Cc2c(C)cccc2S1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC5 Q9UQL6 2/20 0.33
ACHE P22303 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 1/20 0.32
PARP1 P09874 1/20 0.32
PARP10 Q53GL7 1/20 0.32
PARP11 Q9NR21 1/20 0.32
HDAC7 Q8WUI4 1/20 0.31
HTR5A P47898 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5544940 0.79 ADRA2A (0.35) CYP1A2CYP2A6HDAC8ALDH1A1NOTUM
SCHEMBL5537041 0.79 ALDH1A1 (0.33) HDAC8ALDH1A1PARP10PARP11
SCHEMBL4528820 0.79 MEN1 (0.42) MEN1KMT2ACYP1A2CYP2A6HDAC8
SCHEMBL8890449 0.78 KMT2A (0.53) MEN1KMT2AACHEALDH1A1TSHR
SCHEMBL5543688 0.75 ALDH1A1 (0.36) ALDH1A1NOTUM
SCHEMBL2775436 0.70 ALDH1A1 (0.50) MEN1KMT2ACYP1A2ACHEALDH1A1
SCHEMBL10904060 0.68
SCHEMBL5542608 0.67 MEN1 (0.46) MEN1KMT2ACYP1A2CYP2A6HDAC8
SCHEMBL14451090 0.65 HPGD (0.36) MEN1KMT2ACYP1A2CYP2A6ACHE
SCHEMBL8051363 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed