Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976049 | 0.79 | MEN1 (0.38) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL5761154 | 0.77 | CRHBP (0.41) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8890449 | 0.74 | KMT2A (0.53) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL28176472 | 0.73 | KMT2A (0.51) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL10904060 | 0.70 | — | — | |
| SCHEMBL14451090 | 0.67 | HPGD (0.36) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL8528178 | 0.66 | EPHX2 (0.39) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL12998131 | 0.66 | MIF (0.42) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL1498003 | 0.66 | ALDH1A1 (0.59) | MEN1KMT2AACHEALDH1A1KDM4E | |
| SCHEMBL9663954 | 0.66 | ALDH1A1 (0.36) | MEN1KMT2AACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210276952-A1 | NOVEL COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-09-09 | — | — | US | disclosed |
| US-20200392498-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | SOLSTICE BIOLOGICS LTD (IE) | 2020-12-17 | — | — | US | disclosed |
| WO-2019243841-A1 | NOVEL COMPOUNDS | UCL BUSINESS LTD (GB) | 2019-12-26 | — | — | WO | disclosed |
| US-20170114341-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | BRADSHAW CURT W (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170114341-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | BRADSHAW CURT W (US) | 2017-04-27 | — | — | US | disclosed |
| US-20160257961-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING DISULFIDE GROUPS | BRADSHAW CURT W (US) | 2016-09-08 | — | — | US | disclosed |
| US-20160257961-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING DISULFIDE GROUPS | BRADSHAW CURT W (US) | 2016-09-08 | — | — | US | disclosed |
| WO-2015188197-A2 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | SOLSTICE BIOLOGICS, LTD. (IE) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015069932-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING DISULFIDE GROUPS | SOLSTICE BIOLOGICS, LTD. (IE) | 2015-05-14 | — | — | WO | disclosed |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-1947097-A1 | BENZOÝb¨THIOPHEN DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947097-A1 | BENZOÝb¨THIOPHEN DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392498-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | HNRNPC, RNASE1, NSUN3 | MEN1 2230/4885KMT2A 3810/4885ACHE 4827/4885 |
| US-20170114341-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | HNRNPC, RNASE1, NSUN3 | MEN1 2230/4885KMT2A 3810/4885ACHE 4827/4885 |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | CMA1, TPSB2, CTRB1 | MEN1 3812/4885KMT2A 2803/4885ACHE 379/4885 |
| US-20210276952-A1 | NOVEL COMPOUNDS | SERPINC1, SERPINA2, SERPINA3 | MEN1 812/4885KMT2A 4754/4885ACHE 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.