Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.81 |
| ▸ | DRD3 | P35462 | 4/20 | 0.81 |
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256958 | 0.99 | DRD2 (0.79) | DRD2DRD3MAOBADRA1AADRA1B | |
| SCHEMBL9258386 | 0.97 | DRD2 (0.77) | DRD2DRD3MAOBADRA1AADRA1B | |
| SCHEMBL9250065 | 0.92 | DRD2 (0.68) | DRD2DRD3MAOBADRA1AADRA1B | |
| SCHEMBL9256633 | 0.90 | DRD2 (1.00) | DRD2DRD3MAOBHTR1A | |
| SCHEMBL7976323 | 0.87 | DRD2 (0.95) | DRD2DRD3MAOBHTR1A | |
| Hydrochloric Acid SCHEMBL10826808 | 0.86 | DRD2 (0.92) | DRD2DRD3MAOBADRA1BHTR1A | |
| SCHEMBL6777166 | 0.83 | DRD2 (0.57) | DRD2DRD3MAOBACHE | |
| SCHEMBL9360236 | 0.83 | ADRA1B (0.70) | DRD2DRD3ADRA1AADRA1BHTR1A | |
| SCHEMBL10763449 | 0.82 | DRD2 (0.95) | DRD2DRD3MAOBADRA1BHTR1A | |
| SCHEMBL9733689 | 0.81 | DRD2 (0.84) | DRD2DRD3MAOBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5084496-A | Impact resistant thermoplastic molding material | GE PLASTICS JAPAN, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |