Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.38 |
| ▸ | GRM8 | O00222 | 2/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818841 | 0.80 | POLB (0.42) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL9818844 | 0.80 | POLB (0.42) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL27852235 | 0.78 | ALDH1A1 (0.36) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL27581217 | 0.76 | ALDH1A1 (0.35) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL27833984 | 0.76 | ALDH1A1 (0.35) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL27865204 | 0.76 | HTT (0.39) | GRM2GRM3GRM8GRM7GRM4 | |
| SCHEMBL7019518 | 0.76 | GRM2 (0.36) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL4291278 | 0.76 | SGMS2 (0.37) | CYP2C9ATMGRM2GRM3GRM8 | |
| SCHEMBL10764252 | 0.75 | MAOA (0.41) | CYP2C9ATMKDM1AGUSB | |
| SCHEMBL432906 | 0.73 | ALDH1A1 (0.48) | MEN1KMT2AGRM1ALDH1A1EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001045704-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-06-28 | — | — | WO | disclosed |