Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972694 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2PPARAPPARGPTGDR2 | |
| SCHEMBL7528789 | 0.79 | KDM4E (0.38) | SMN1; SMN2PPARGPTGDR2ALDH1A1 | |
| SCHEMBL7974243 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARAPPARGPTGDR2PPARD | |
| SCHEMBL7976476 | 0.76 | PPARA (0.42) | SMN1; SMN2PPARAPPARGPTGDR2PPARD | |
| SCHEMBL4815922 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARAPPARGPTGDR2PPARD | |
| SCHEMBL7974342 | 0.69 | PPARA (0.38) | SMN1; SMN2PPARAPPARGPTGDR2PPARD | |
| SCHEMBL7972569 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2PPARAPPARGPTGDR2ALDH1A1 | |
| SCHEMBL4817468 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARAPPARGPTGDR2PPARD | |
| SCHEMBL11359371 | 0.67 | SMN1; SMN2 (0.73) | SMN1; SMN2PPARAPPARGALDH1A1 | |
| SCHEMBL7962763 | 0.66 | LMNA (0.42) | SMN1; SMN2PPARAPPARGPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |