Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 3/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.47 |
| ▸ | GRM6 | O15303 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978440 | 0.87 | GRM8 (0.54) | ALDH1A1CYP3A4TSHRTDP1GRM8 | |
| SCHEMBL7245339 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL3949842 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL7976506 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1GRM8GRM4GRM6KMT2A | |
| SCHEMBL31481066 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL7976616 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C19GRM8GRM4 | |
| SCHEMBL7246635 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL31584827 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRTDP1GRM8 | |
| SCHEMBL2432560 | 0.82 | GPR35 (0.45) | ALDH1A1CYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL29192875 | 0.78 | GRM8 (0.52) | ALDH1A1CYP3A4TSHRTDP1GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055138-A1 | AZOLE DERIVATIVES, THEIR PREPARATION AND USE | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |