SCHEMBL7976546

SCHEMBL7976546

COC(=O)C(F)c1ccc(O)c(N)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.51
GAA P10253 6/20 0.51
ALOX12 P18054 1/20 0.51
HTT P42858 1/20 0.51
HIF1A Q16665 1/20 0.51
HSD17B10 Q99714 3/20 0.50
ALOX15 P16050 2/20 0.50
PKM P14618 2/20 0.50
USP2 O75604 1/20 0.50
HPGD P15428 1/20 0.50
GFER P55789 1/20 0.46
MAPT P10636 4/20 0.42
BLM P54132 2/20 0.42
MEN1 O00255 2/20 0.42
RECQL P46063 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
THRB P10828 1/20 0.42
MCL1 Q07820 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2433161 0.87 MT-CO2 (0.38) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL9619872 0.82 ALDH1A1 (0.53) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL11216724 0.82 ALDH1A1 (0.58) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL31430560 0.82 ALDH1A1 (0.58) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL7708885 0.81 HDAC1 (0.42) ALDH1A1GAAHSD17B10ALOX15HPGD
SCHEMBL7714952 0.78 SLC6A3 (0.46) ALDH1A1GAAHTTMAPTKMT2A
SCHEMBL6034588 0.77 KMT2A (0.46) GAAHIF1ABLMMEN1KMT2A
SCHEMBL7976616 0.76 ALDH1A1 (0.46) ALDH1A1GAAHSD17B10ALOX15USP2
SCHEMBL27441057 0.75 ESR1 (0.54) KMT2ACA12CA1CA2CA9
SCHEMBL13140163 0.75 ALDH1A1 (0.59) ALDH1A1GAAALOX12HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001055138-A1 AZOLE DERIVATIVES, THEIR PREPARATION AND USE SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed