Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870950 | 0.91 | OPRD1 (0.41) | OPRD1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5871129 | 0.85 | RPLP1 (0.42) | OPRD1SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL5870905 | 0.82 | CHRM1 (0.41) | OPRD1 | |
| SCHEMBL7498243 | 0.81 | OPRD1 (0.44) | OPRD1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5871033 | 0.81 | OPRD1 (0.44) | OPRD1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7503837 | 0.81 | OPRD1 (0.44) | OPRD1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5871054 | 0.80 | CHRM2 (0.39) | KMT2ASLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL7501264 | 0.79 | OPRD1 (0.42) | OPRD1KMT2ASLC6A3OPRM1SIGMAR1 | |
| SCHEMBL3278539 | 0.79 | TRPM8 (0.46) | OPRD1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3273608 | 0.79 | TRPM8 (0.46) | OPRD1KMT2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092226-A1 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHOD OF USE THEREOF | SEPRACOR, INC. (US) | 2001-12-06 | — | — | WO | disclosed |