Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976858 | 0.94 | L3MBTL1 (0.61) | L3MBTL1KMT2AMEN1POLBGSK3B | |
| SCHEMBL7978680 | 0.88 | L3MBTL1 (0.73) | L3MBTL1KMT2AMEN1POLBGSK3B | |
| SCHEMBL7981607 | 0.88 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1POLBMAPT | |
| SCHEMBL7976975 | 0.82 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12309829 | 0.80 | MAPT (0.49) | L3MBTL1KMT2AMEN1POLBMAPT | |
| SCHEMBL7978822 | 0.79 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1POLBMAPT | |
| SCHEMBL11090178 | 0.77 | ALDH1A1 (0.49) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL7976868 | 0.76 | KMT2A (0.47) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9503768 | 0.74 | L3MBTL1 (0.68) | L3MBTL1KMT2AMEN1GSK3BMAPT | |
| SCHEMBL7978676 | 0.74 | ALDH1A1 (0.52) | L3MBTL1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |