Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LDHB | P07195 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976858 | 0.93 | L3MBTL1 (0.61) | L3MBTL1KMT2AALOX5ALDH1A1MAPT | |
| SCHEMBL7978680 | 0.88 | L3MBTL1 (0.73) | L3MBTL1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7965237 | 0.88 | L3MBTL1 (0.55) | L3MBTL1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7978822 | 0.86 | L3MBTL1 (0.54) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7976868 | 0.83 | KMT2A (0.47) | L3MBTL1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL12309829 | 0.82 | MAPT (0.49) | L3MBTL1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7976975 | 0.82 | L3MBTL1 (0.55) | L3MBTL1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL28641204 | 0.80 | MAPT (0.72) | L3MBTL1KMT2AALOX5ALDH1A1MAPT | |
| SCHEMBL11090178 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTGAALMNA | |
| SCHEMBL2880324 | 0.79 | KMT2A (0.57) | KMT2AALDH1A1MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |