SCHEMBL7976944

SCHEMBL7976944

O=C1NN=C(c2ccc(N3C=CC3)cc2)CO1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.51
PDE3A Q14432 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261632 0.75 PDE3A (0.65) PDE3BPDE3A
SCHEMBL4693648 0.75 PDE3B (0.70) PDE3BPDE3A
SCHEMBL4649731 0.75 PDE3B (0.59) PDE3BPDE3A
SCHEMBL7976918 0.75 PDE3B (0.70) PDE3BPDE3A
SCHEMBL251865 0.75 PDE3B (0.67) PDE3BPDE3A
SCHEMBL9669173 0.72 PDE3B (0.52) PDE3BPDE3A
SCHEMBL20702701 0.72 PDE3B (0.86) PDE3BPDE3A
SCHEMBL7979367 0.71 PDE3B (0.51) PDE3BPDE3A
SCHEMBL11248109 0.70 PDE3B (0.50) PDE3BPDE3A
SCHEMBL20702677 0.69 PDE3A (0.75) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001000601-A1 NOVEL 4-(2-OXODIHYDROOXADIAZINYLPHENYL)AMIDES AND THE USE THEREOF FOR TREATING ANEMIA BAYER AKTIENGESELLSCHAFT (DE) 2001-01-04 WO disclosed