Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | PTAFR | P25105 | 10/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966194 | 1.00 | CACNA2D1 (0.41) | CACNA2D1PTAFRNOS1TBXAS1POLB | |
| SCHEMBL7982584 | 0.85 | CCNC (0.40) | PTAFRTBXAS1POLBHPGD | |
| SCHEMBL7982586 | 0.85 | CCNC (0.40) | PTAFRTBXAS1POLBHPGD | |
| SCHEMBL7982565 | 0.82 | POLB (0.40) | PTAFRPOLBHPGD | |
| SCHEMBL7982583 | 0.81 | CYP1A2 (0.47) | PTAFRPOLBHPGDNAMPT | |
| SCHEMBL7982797 | 0.81 | CYP1A2 (0.47) | PTAFRPOLBHPGDNAMPT | |
| SCHEMBL7966412 | 0.81 | USP2 (0.44) | POLBNAMPT | |
| SCHEMBL7982982 | 0.77 | FKBP1A (0.47) | — | |
| SCHEMBL7982986 | 0.77 | FKBP1A (0.47) | — | |
| SCHEMBL7979920 | 0.75 | POLB (0.43) | PTAFRPOLBHPGDNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |