Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | PCNA | P12004 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982982 | 1.00 | FKBP1A (0.47) | FKBP1ACCNCCDK8CYP4F2CYP4A11 | |
| SCHEMBL7966412 | 0.85 | USP2 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL7976695 | 0.83 | RAB9A (0.46) | CCNCCDK8MEN1KMT2AALDH1A1 | |
| SCHEMBL7982584 | 0.81 | CCNC (0.40) | CCNCCDK8CYP4F2CYP4A11 | |
| SCHEMBL7982586 | 0.81 | CCNC (0.40) | CCNCCDK8CYP4F2CYP4A11 | |
| Oxalic Acid SCHEMBL7978632 | 0.80 | MAPT (0.43) | CCNCCDK8MEN1KMT2AALDH1A1 | |
| SCHEMBL7976690 | 0.79 | USP2 (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7976964 | 0.77 | CACNA2D1 (0.41) | — | |
| SCHEMBL7966194 | 0.77 | CACNA2D1 (0.41) | — | |
| SCHEMBL7982543 | 0.76 | ALDH1A1 (0.43) | C3AR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |