Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982586 | 1.00 | CCNC (0.40) | CCNCCDK8HSD17B1HSD17B2POLB | |
| SCHEMBL7966194 | 0.85 | CACNA2D1 (0.41) | POLBHPGDPTAFRTBXAS1 | |
| SCHEMBL7976964 | 0.85 | CACNA2D1 (0.41) | POLBHPGDPTAFRTBXAS1 | |
| SCHEMBL7978383 | 0.82 | LMNA (0.46) | POLBHPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7978380 | 0.82 | LMNA (0.46) | POLBHPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7982986 | 0.81 | FKBP1A (0.47) | CCNCCDK8CYP4F2CYP4A11 | |
| SCHEMBL7982982 | 0.81 | FKBP1A (0.47) | CCNCCDK8CYP4F2CYP4A11 | |
| SCHEMBL7982583 | 0.81 | CYP1A2 (0.47) | POLBHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7982797 | 0.81 | CYP1A2 (0.47) | POLBHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7979963 | 0.79 | PTAFR (0.47) | POLBHPGDSMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |