Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972863 | 0.84 | HRH3 (0.46) | NFE2L2HRH3 | |
| SCHEMBL7972868 | 0.84 | HRH3 (0.41) | NFE2L2HRH3 | |
| SCHEMBL7973158 | 0.82 | MEN1 (0.46) | — | |
| SCHEMBL7974462 | 0.78 | MAPT (0.47) | HRH3 | |
| SCHEMBL7961502 | 0.77 | MAOB (0.40) | SIGMAR1NFE2L2HRH3 | |
| SCHEMBL7971371 | 0.77 | HRH3 (0.44) | SIGMAR1HRH3 | |
| SCHEMBL30674540 | 0.76 | NFE2L2 (0.70) | NFE2L2HRH3 | |
| SCHEMBL16838748 | 0.73 | NFE2L2 (0.56) | NFE2L2 | |
| SCHEMBL4326032 | 0.73 | NPY1R (0.50) | SIGMAR1NFE2L2 | |
| SCHEMBL7961186 | 0.73 | HTR1A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |