Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973158 | 0.86 | MEN1 (0.46) | L3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7974701 | 0.82 | L3MBTL1 (0.47) | MAPTKCNH2HRH3TDP1L3MBTL1 | |
| SCHEMBL7972769 | 0.82 | MAPT (0.47) | MAPTKCNH2HRH3TDP1L3MBTL1 | |
| SCHEMBL7317389 | 0.82 | KCNH2 (0.56) | MAPTKCNH2HRH3TDP1L3MBTL1 | |
| SCHEMBL944258 | 0.80 | TDP1 (0.51) | KCNH2HRH3TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9196956 | 0.79 | TDP1 (0.50) | KCNH2HRH3TDP1L3MBTL1 | |
| SCHEMBL7972868 | 0.78 | HRH3 (0.41) | HRH3 | |
| SCHEMBL7977073 | 0.78 | SIGMAR1 (0.44) | HRH3 | |
| SCHEMBL9381992 | 0.76 | KCNH2 (0.50) | MAPTKCNH2HRH3TDP1L3MBTL1 | |
| SCHEMBL9591899 | 0.76 | TDP1 (0.52) | MAPTKCNH2HRH3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |