Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974823 | 0.81 | ALDH1A1 (0.47) | KMT2AMEN1GAACTSKALDH1A1 | |
| SCHEMBL7963528 | 0.75 | TDP1 (0.36) | TDP1ATMNPSR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7788056 | 0.75 | TDP1 (0.42) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL7977002 | 0.75 | CTSK (0.46) | CTSK | |
| SCHEMBL7963488 | 0.73 | ALDH1A1 (0.51) | TDP1ATMNPSR1MAPTKDM4E | |
| SCHEMBL7973799 | 0.73 | ALDH1A1 (0.37) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL7945007 | 0.72 | TDP1 (0.46) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL29335806 | 0.72 | TDP1 (0.41) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL7974856 | 0.71 | CTSK (0.43) | CTSK | |
| SCHEMBL24511096 | 0.71 | TDP1 (0.53) | TDP1ATMNPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |