Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979966 | 0.88 | ACE (0.46) | FKBP1A | |
| SCHEMBL7976681 | 0.82 | KMT2A (0.43) | FKBP1APTPN1KMT2A | |
| SCHEMBL7966698 | 0.79 | FKBP1A (0.67) | FKBP1A | |
| SCHEMBL7250340 | 0.71 | FKBP1A (0.82) | FKBP1A | |
| SCHEMBL7983145 | 0.70 | ACE (0.54) | FKBP1A | |
| SCHEMBL7980422 | 0.70 | ACE (0.54) | FKBP1A | |
| SCHEMBL7980051 | 0.69 | OPRM1 (0.55) | FKBP1AKMT2A | |
| SCHEMBL2004442 | 0.69 | FKBP1A (0.92) | FKBP1A | |
| SCHEMBL15048988 | 0.69 | FKBP1A (0.92) | FKBP1A | |
| SCHEMBL4679960 | 0.68 | FKBP1A (1.00) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323215-B1 | TREAT AND PREVENT DISORDERS CHARACTERIZED BY NEURONAL DAMAGE SUCH AS PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, STROKE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, DIABETIC NEUROPATHY AND BELL'S PALSY. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-11-27 | — | — | US | disclosed |