Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779192 | 0.88 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3421847 | 0.86 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL29605396 | 0.86 | L3MBTL1 (0.60) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL25068054 | 0.81 | L3MBTL1 (0.67) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6588776 | 0.80 | L3MBTL1 (0.72) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1760381 | 0.77 | ALDH1A1 (0.52) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8425035 | 0.76 | MEN1 (0.62) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11780284 | 0.74 | ACHE (0.65) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL31633459 | 0.73 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1HPGDMAPT | |
| Methane SCHEMBL28329643 | 0.73 | MEN1 (0.60) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143317-A1 | TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS | WYETH (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009143313-A1 | TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS | WYETH (US) | 2009-11-26 | — | — | WO | disclosed |