SCHEMBL3421847

SCHEMBL3421847

Nc1ccc(-c2nc(Cl)nc(Cl)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.50
KMT2A Q03164 7/20 0.50
ALDH1A1 P00352 7/20 0.50
NPC1 O15118 6/20 0.50
RAB9A P51151 6/20 0.50
HPGD P15428 5/20 0.50
MAPT P10636 5/20 0.50
KDM4E B2RXH2 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
TP53 P04637 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP19A1 P11511 1/20 0.45
HTT P42858 1/20 0.43
LMNA P02545 4/20 0.43
GLA P06280 3/20 0.43
ATM Q13315 1/20 0.43
PIK3R1 P27986 1/20 0.42
PIK3CA P42336 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977423 0.86 L3MBTL1 (0.50) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL8425035 0.84 MEN1 (0.62) MEN1KMT2AALDH1A1NPC1RAB9A
Methane SCHEMBL28329643 0.82 MEN1 (0.60) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL31633459 0.82 ALDH1A1 (0.69) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL11400612 0.80 NPC1 (0.60) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL25875264 0.80 MEN1 (0.54) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL10498625 0.79 MEN1 (0.53) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL12474645 0.77 NFKB1 (0.53) NPC1RAB9AHPGDMAPTKDM4E
SCHEMBL6016966 0.76 TXN (0.55) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL16332656 0.76 L3MBTL1 (0.54) MEN1KMT2AALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US claimed
US-10870724-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-22 US disclosed
US-10774216-B2 Resin composition and uses of the same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2020-09-15 US disclosed
US-10513607-B2 Resin composition and uses of the same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2019-12-24 US disclosed
US-10465037-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-05 US disclosed
US-20190144666-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2019-05-16 US disclosed
US-20180030267-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2018-02-01 US disclosed
US-20170260365-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2017-09-14 US disclosed
US-20170158806-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-08 US disclosed
EP-3172201-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC Global Technologies B.V. (NL) 2017-05-31 EP disclosed
WO-2007044312-A1 POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (US) 2007-04-19 WO disclosed
US-20070080330-A1 Flame retardant composition and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-04-12 US disclosed
US-20070082986-A1 Polymer composition, method, and article SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-04-12 US disclosed
US-20070082987-A1 Poly(arylene ether) composition, method, and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-04-12 US disclosed
EP-0059434-B2 Multi-layer printed circuit board and process for production thereof HITACHI LTD (JP) 1999-08-25 EP disclosed
EP-0582687-A4 PERMANENTLY STAIN RESISTANT TEXTILE FIBERS. PEACH STATE LABS INC (US) 1994-12-14 EP disclosed
US-5316850-A Permanently stain resistant textile fibers PEACH STATE LABS, INC. (US) 1994-05-31 US disclosed
EP-0582687-A1 PERMANENTLY STAIN RESISTANT TEXTILE FIBERS PEACH STATE LABS, INC. (US) 1994-02-16 EP disclosed
WO-1992018332-A1 PERMANENTLY STAIN RESISTANT TEXTILE FIBERS PEACH STATE LABS, INC. (US) 1992-10-29 WO disclosed
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10870724-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, EPHX2 MEN1 3092/4885KMT2A 4211/4885ALDH1A1 318/4885
US-20170158806-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF HSP90AA1, HSP90AB1, EPHX2 MEN1 3092/4885KMT2A 4211/4885ALDH1A1 318/4885
US-10465037-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB2P, HSP90AB1 MEN1 3244/4885KMT2A 4298/4885ALDH1A1 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.