Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067653 | 0.79 | HTR1A (0.37) | HTR1A | |
| SCHEMBL10390219 | 0.79 | HTR1A (0.37) | HTR1A | |
| SCHEMBL10390238 | 0.76 | HTR1A (0.38) | HTR1A | |
| SCHEMBL1752693 | 0.75 | HTR1A (0.41) | SIGMAR1HTR1A | |
| SCHEMBL3433317 | 0.72 | DRD2 (0.36) | SIGMAR1HTR1A | |
| SCHEMBL1634692 | 0.69 | CYP11B2 (0.41) | GRIN2BSIGMAR1PRCP | |
| SCHEMBL3653495 | 0.68 | PLAU (0.41) | GRIN2B | |
| SCHEMBL1383876 | 0.68 | ANPEP (0.39) | — | |
| SCHEMBL2183528 | 0.68 | PDPK1 (0.37) | — | |
| SCHEMBL6026793 | 0.67 | SIGMAR1 (0.54) | SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313117-B1 | TREATING AUTOIMMUNE DISORDERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2001-11-06 | — | — | US | claimed |