Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975212 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| SCHEMBL7974388 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| Water SCHEMBL6484487 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2RAB9ANPC1KMT2ALMNA | |
| Water SCHEMBL6484483 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2RAB9ANPC1KMT2ALMNA | |
| SCHEMBL7964121 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| SCHEMBL7964010 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| SCHEMBL599742 | 0.75 | CYP2C9 (0.72) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| SCHEMBL9834816 | 0.74 | RAB9A (0.58) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| SCHEMBL2996519 | 0.73 | AR (0.77) | SMN1; SMN2ARRAB9ANPC1KMT2A | |
| SCHEMBL10333344 | 0.73 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |